2020;16(3):458-462. Taking peony along with estrogen might increase the effects and side effects from estrogen. J Am Acad Dermatol 2011;65(4):699-714. Liquorice supplements View abstract. Riv Patol Nerv Ment 1983;104(4):179-183. View abstract. Brasseur, A. and Ducobu, J. 1979;14(5):605-607. Volatiles with antimicrobial activity from the roots of Greek Paeonia taxa. View abstract. Severe hypokalaemia with paralysis induced by small doses of liquorice. It combined licorice, dates, peonies, and skullcap, and was traditionally prepared as a tea. 2020;2020:3727682. MacKenzie, M. A., Hoefnagels, W. H., Jansen, R. W., Benraad, T. J., and Kloppenborg, P. W. The influence of glycyrrhetinic acid on plasma cortisol and cortisone in healthy young volunteers. J Pharmacobiodyn 1984;7:304-11. Pharm Biol 2021;59(1):1276-1285. Am J Chin Med 1996;24:165-8. Gatica-Ortega ME, Pastor-Nieto MA. View abstract. Microbiol Immunol 2000;44(9):799-804. J Intern Med 1999;245:307-10. 2010 Nov;35(10):1587-93. Side effects of peony tea! A systemic review and meta-analysis of the clinical efficacy and safety of total glucosides of peony combined with methotrexate in rheumatoid arthritis. View abstract. A., van der Ven, P. F., Martin, M., Sherman, J., and Haley, J. J Clin Periodontol 1991;18(3):210-212. A controlled trial of a dissolving oral patch concerning glycyrrhiza (licorice) herbal extract for the treatment of aphthous ulcers. Clinical reduction of S. mutans in pre-school children using a novel liquorice root extract lollipop: a pilot study. View abstract. View abstract. Goto, F., Asama, Y., and Ogawa, K. Sho-saiko-to-ka-kikyo-sekko as an alternative treatment for chronic tonsillitis to avoid surgery. Muscle cramps.Early research suggests that taking a specific combination of peony and licorice (Shakuyaku-kanzoh-to) might ease muscle cramps in people with liver cirrhosis and in people undergoing hemodialysis. Anesth Analg. We currently have no information for PEONY overview. View abstract. Psychoneuroendocrinology. Antiviral Res 1987;7(3):127-137. Gallacher SD, Tsokolas G, Dimitropoulos I. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department. Lin, J. C. Mechanism of action of glycyrrhizic acid in inhibition of Epstein-Barr virus replication in vitro. View abstract. van Beers, E. J., Stam, J., and van den Bergh, W. M. Licorice consumption as a cause of posterior reversible encephalopathy syndrome: a case report. Tamir S, Eizenberg M, Somjen D, et al. Mitscher, L. A., Park, Y. H., Clark, D., and Beal, J. L. Antimicrobial agents from higher plants. Nutr Res 2012;32(2):85-92. In general, the safety and effectiveness of alternative medicines have not been scientifically proven and remain largely unknown. Qraa Advanced Lacto Dark Underarm Whitening Cream Product Claims Qraa underarm whitening cream claims to lighten dark underarms by reducing melanin from the skin in the area. Because children's skin is soft and tender, more sufficient data on side effects such as allergies or burns, are needed. Contact Dermatitis Due to Paeonia (Peony). Am J Psychiatry 1994;151:617-8. A dose of 800 milligrams (mg) or more of licorice root per day has been linked to low potassium levels. Peony might have some of the same effects as estrogen. Akamatsu, H., Komura, J., Asada, Y., and Niwa, Y. J Clin Endocrinol Metab 1990;70(6):1637-1643. Dai DW, Singh I, Hershman JM. The combination of licorice and white peony can help to decrease the excess testosterone that is being produced by the ovaries in PCOS. B. Licorice-associated reversible cerebral vasoconstriction with PRES. This might decrease the effects of midazolam. View abstract. Pharm Biol. Loop diuretics can also decrease potassium levels. View abstract. Teelucksingh S, Mackie AD, Burt D, McIntyre MA, Brett L, Edwards CR. Licorice that has the active ingredient of glycyrrhiza can have serious side effects. Exp Ther Med 2016;11(3):1135-41. Gibertoni, M., Bonito, V., Colombo, A., Falasca, A., and Nichelli, P. [Licorice-induced myopathy. Contact Dermatitis 1999;40(1):56. Lancet 2003;361:2045-6.. View abstract. Ruetzler K, Fleck M, Nabecker S, Pinter K, Landskron G, Lassnigg A, You J, Sessler DI. J Altern Complement Med. BMJ Case Rep. 2013 Sep 19;2013. Am J Med Sci 2003;325:153-6. *. Endocrinol Jpn 1990;37:331-41. Some medications are changed and broken down by the liver. View abstract. Pakravan F, Salehabad NH, Karimi F, Isfahani MN. Lozano, P., Flores, D., Martinez, S., Artigues, I., Rimbau, E. M., and Gomez, F. Upper limb ischemia induced by chronic licorice ingestion. View abstract. Sucking on a licorice lozenge or gargling with a licorice fluid shortly before placement of a breathing tube seems to help prevent cough and. Chang GH, Lin YS, Hsu KH, et al. Int J Environ Res Public Health 2021;19(1):242. J Altern Complement Med 2000;6:557-9. October 15, 2021. Phytother Res. Efficiency and safety of desloratadine in combination with compound glycyrrhizin in the treatment of chronic urticaria: a meta-analysis and systematic review of randomised controlled trials. Robles BJ, Sandoval AR, Dardon JD, Blas CA. Acute myopathy associated with chronic licorice ingestion: reversible loss of myoadenylate deaminase activity. [Clinical characteristics of five elderly patients with severe hypokalemia induced by glycyrrhizin derivatives]. What are the side-effects of taking liquorice? Phytother Res. This is a partial list of herbs and herbal treatments with known or suspected adverse effects, either alone or in interaction with other herbs or drugs.Non-inclusion of an herb in this list does not imply that it is free of adverse effects. View abstract. View abstract. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(4):358-360. N Engl J Med 1990;322:850. View abstract. A. . Intern Med 2017;56(2):175-9. View abstract. Takahara T, Watanabe A, Shiraki K. Effects of glycyrrhizin on hepatitis B surface antigen: a biochemical and morphological study. Neurology 2010;75(21):1939-1941. Licorice root is aromatic and is used as a flavoring agent in tea and other beverages. Astragalus may interact with medications that suppress the . 2008;9(3):88-98. Sheehan M, Rustin MHA, Atherton DJ, et al. View abstract. 2005 - 2023 WebMD LLC. Davis EA, Morris DJ. Effect of deglycyrrhizinated liquorice on gastric mucosal damage by aspirin. Fiore, C., Eisenhut, M., Krausse, R., Ragazzi, E., Pellati, D., Armanini, D., and Bielenberg, J. Antiviral effects of Glycyrrhiza species. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. "Water pills" can also decrease potassium levels. View abstract. 5-10-2004;208(1):89-94. Some of these health benefits have also . PCOS; Fertility; 25 - 45; Menopause; 45 - 60; Pregnancy "It contains liquiritin, an active compound that helps to disperse and remove existing melanin in the skin," explains Chwalek. Yoon JY, Cha JM, Hong SS, et al. van Rossum, T. G., Vulto, A. G., Hop, W. C., Brouwer, J. T., Niesters, H. G., and Schalm, S. W. Intravenous glycyrrhizin for the treatment of chronic hepatitis C: a double-blind, randomized, placebo-controlled phase I/II trial. Arentz S, Smith CA, Abbott J, Fahey P, Cheema BS, Bensoussan A. Eisenburg, J. Chen, W. G. and Ba, Z. M. Prof. ZHANG Yi's experience in treating severe arrhythmia. View abstract. Leem, K., Kim, H., Boo, Y., Lee, H. S., Kim, J. S., Yoo, Y. C., Ahn, H. J., Park, H. J., Seo, J. C., Kim, H. K., Jin, S. Y., Park, H. K., Chung, J. H., and Cho, J. J. Adjuvant role of a new emollient cream in patients with palmar and/or plantar psoriasis: a pilot randomized open-label study. It is often used together with peony, which can significantly enhance . Pharmazie 2010;65(8):624-8. View abstract. An unusual cause of hypokalemic paralysis: chronic licorice ingestion. Licorice might decrease how well cisplatin works. View abstract. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract in vitro by HPLC-DAD and HPLC-ESI/MS analyses. View abstract. [Protective mechanism of Salvia miltiorrhiza and Paeonia lactiflora for experimental liver damage]. A Rutgers expert discusses how eating black licorice can affect your health. View abstract. Pathogenetic considerations and presentation of a clinical case]. O'Connell K, Kinsella J, McMahon C, Holian J, O'Riordan S. Posterior reversible encephalopathy syndrome (PRES) associated with liquorice consumption. Hossain, M. S., Takimoto, H., Hamano, S., Yoshida, H., Ninomiya, T., Minamishima, Y., Kimura, G., and Nomoto, K. Protective effects of hochu-ekki-to, a Chinese traditional herbal medicine against murine cytomegalovirus infection. Zhongguo Zhong Xi Yi Jie He Za Zhi. Medicinal uses of licorice through the millennia: the good and plenty of it. Contact Dermatitis 1989; 20:152-3.. View abstract. View abstract. Side effects, toxicity, and interactions. Sakamoto, S., Yoshino, H., Shirahata, Y., Shimodairo, K., and Okamoto, R. Pharmacotherapeutic effects of kuei-chih-fu-ling-wan (keishi-bukuryo-gan) on human uterine myomas. Apparantly it's the one most important thing that shouldn't mix with Prednisolone and it makes withdrawal symptoms much worse. View abstract. Z Kardiol 1991;80(6):389-391. Prospective study]. . Int Hepatol Comm 1997;233-238. View abstract. Sigurjonsdottir HA, Ragnarsson J, Franzson L, Sigurdsson G. Is blood pressure commonly raised by moderate consumption of liquorice? View abstract. J Clin Psychopharmacol 2008;28(3):264-370. The invention belongs to the field of biopesticides, and mainly discloses a nuisanceless biological compound pesticide and a preparation method thereof. View abstract. Gut 1973;14(9):711-715. Barrella, M., Lauria, G., Quatrale, R., and Paolino, E. Hypokaliemic rhabdomyolysis associated with liquorice ingestion: report of an atypical case. 1. View abstract. Hyodo T, Taira T, Kumakura M, et al. View abstract. It contains kojic acid, witch hazel, and licorice extracts that reduce melanin production and exfoliate . An Bras Dermatol 2010;85(5):613-620. Hypertension and the cortisol-cortisone shuttle. Yu IC, Tsai YF, Fang JT, Yeh MM, Fang JY, Liu CY. N Engl J Med 1968;278(25):1381-1383. View abstract. View abstract. Hawrelak, J. Licorice, tobacco chewing, and hypertension. Yamada, K., Kanba, S., Yagi, G., and Asai, M. Effectiveness of herbal medicine (shakuyaku-kanzo-to) for neuroleptic-induced hyperprolactinemia. Pak J Med Sci 2022;38(1):271-275. 2020. Am J Respir.Cell Mol.Biol. Inflammopharmacology 2022;30(2):477-486. Med Princ Pract 2010;19(6):485-489. Drug Metab Dispos 2002;30:709-15.. View abstract. Fatal hypokalaemic alkalosis with tetany during liquorice and P.A.S. Akbari N, Asadimehr N, Kiani Z. Clin Med (Lond) 2017;17(1):43-5. Kinoshita T, Maruyama K, Yamamoto N, Saito I. Ha Y, Wang T, Li J, et al. Chinese peony root comes in two different forms. View abstract. [Clinical study on treatment of mid-advanced crescentic nephritis by qingre huoxue recipe]. The efficacy and safety of total glucosides of peony in the treatment of primary Sjögren's syndrome: a multi-center, randomized, double-blinded, placebo-controlled clinical trial. Taking licorice along with "water pills" might make potassium levels drop too low. View abstract. Nasal irrigation with Glycyrrhiza glabra extract for treatment of allergic rhinitis - A study of in vitro, in vivo and clinical trial. Turpie AG, Runcie J, Thomson TJ. Prudden JF. 2000;19(8):434-439. 2020;50:102401. Chinese herbal medicine for atopic eczema. View abstract. Hasegawa, J., Suyama, Y., Kinugawa, T., Morisawa, T., and Kishimoto, Y. Echocardiographic findings of the heart resembling dilated cardiomyopathy during hypokalemic myopathy due to licorice-induced pseudoaldosteronism. View abstract. Fujisawa, Y., Sakamoto, M., Matsushita, M., Fujita, T., and Nishioka, K. Glycyrrhizin inhibits the lytic pathway of complement--possible mechanism of its anti-inflammatory effect on liver cells in viral hepatitis. Zhongguo Zhong.Xi.Yi Jie.He.Za Zhi 2008;28(12):1090-1092. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Li G, Simmler C, Chen L, et al. Doeker, B. M. and Andler, W. Liquorice, growth retardation and Addison's disease. View abstract. Ohta H, Ni JW, Matsumoto K, et al. The immediate effect of Shakuyaku-kanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. A randomized, crossover comparison of herbal medicine and bromocriptine against risperidone-induced hyperprolactinemia in patients with schizophrenia. View abstract. Cooper, H., Bhattacharya, B., Verma, V., McCulloch, A. J., Smellie, W. S., and Heald, A. H. Liquorice and soy sauce, a life-saving concoction in a patient with Addison's disease. 2011;25(1-2):21-38. Armanini, D., Nacamulli, D., Francini-Pesenti, F., Battagin, G., Ragazzi, E., and Fiore, C. Glycyrrhetinic acid, the active principle of licorice, can reduce the thickness of subcutaneous thigh fat through topical application. Biol Pharm Bull 1998;21:1277-81. 2005;25(6):540-542. Brouwers, A. J. and van der, Meulen J. Although white peony is generally considered safe for most people, drinking large amounts might have some negative consequences. Chien, C. F., Wu, Y. T., and Tsai, T. H. Biological analysis of herbal medicines used for the treatment of liver diseases. 2013 Jun;22(2):173-8. Unfortunately, there is not much scientific evidence around the use of Licorice in Hirsutism, and more studies are needed to prove if it's effective in hirsutism or not. View abstract. Acharya SK, Dasarathy S, Tandon A, et al. View abstract. 1993;13(10):591-3, 579. Treatment of duodenal ulcer with glycyrrhizinic-acid-reduced liquorice. Kumada T, et al. J Clin Pharm Ther 2002;27:229-30. . View abstract. Tewari SN, Wilson AK. Int Urol Nephrol. 2019;18(Suppl1):291-301. J Cancer Res Ther. Select a condition to view a list of vitamins. The glycyrrhizin and glycyrrhetic acid constituents of licorice have significant anti-androgen effects, 32-34 which may be helpful in reducing androgenic symptoms in women with PCOS. White peony ( bai shao in Chinese) is root without any bark, while red peony . Clinical application of compound Glycyrrhizin tablets in the treatment of patients with Simplex Henoch-Schonlein Purpura and its effect on immune function. Hukkanen J, Ukkola O, Savolainen MJ. Eur J Pharmacol 11-7-2005;524(1-3):111-119. Janse A, van Iersel M, Hoefnagels WH, Olde Rikker MG. View abstract. Fung AY, Look PC, Chong LY, et al. 2020;45(2):257-264. View abstract. Suzuki H, Ohta Y, Takino T, and et al. View abstract. Nahidi F, Zare E, Mojab F, Alavi-Majd H. Effects of licorice on relief and recurrence of menopausal hot flashes. J Peripher.Nerv.Syst. J Contemp.Dent Pract. Rikknen K, Seckl JR, Heinonen K, Pyhl R, Feldt K, Jones A, Pesonen AK, Phillips DI, Lahti J, Jrvenp AL, Eriksson JG, Matthews KA, Strandberg TE, Kajantie E. Maternal prenatal licorice consumption alters hypothalamic-pituitary-adrenocortical axis function in children. View abstract. 2010;33(2):321-324. Indian J Dent Res 2010;21(3):380-384. View abstract. View abstract. Since the content of glycyrrhizin is either decreased or removed from the DGL licorice supplement, its positive effects on PCOS may also be reduced. View abstract. View abstract. Balakrishnan, V., Pillai, M. V., Raveendran, P. M., and Nair, C. S. Deglycyrrhizinated liquorice in the treatment of chronic duodenal ulcer. View abstract. View abstract. A multicentre trial. Zhu Q, Qi X, Wu Y, Wang K. Clinical study of total glucosides of paeony for the treatment of diabetic kidney disease in patients with diabetes mellitus. 2017 Sep;31(9):1330-1340. Effects of glycyrrhizin on the pharmacokinetics of nobiletin in rats and its potential mechanism. Peony root might decrease the amount of phenytoin in the body. View abstract. Complement Ther Med. Glycyrrhizin, an active component of liquorice roots, and replication of SARS-associated coronavirus. Licorice-Induced Hypokalemia: A Case Report. Eur Neurol 1992;32(1):44-51. Licorice reduces body fat mass in obese men and women. Guo TL, Zhou XW. van Rossum, T. G., Vulto, A. G., Hop, W. C., and Schalm, S. W. Pharmacokinetics of intravenous glycyrrhizin after single and multiple doses in patients with chronic hepatitis C infection. View abstract. View abstract. Petramfar P, Hajari F, Yousefi G, Azadi S, Hamedi A. Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial. View abstract. View abstract. Complement Ther Clin Pract. A. and Cunliffe, W. J. Self-medication with liquorice in a patient with Addison's disease. View abstract. View abstract. 30. No negative side effects. Horm.Res 1999;52(5):253-255. Peony-glycyrrhiza decoction for antipsychotic-related hyperprolactinemia in women with schizophrenia: a randomized controlled trial. However, taking too much licorice root may cause side effects. J Ethnopharmacol 2002;81:101-4.. View abstract. J Ethnopharmacol 2004;94:339-44. . J Clin Psychopharmacol 1997;17(3):234-235. Nabeshima, S., Kashiwagi, K., Ajisaka, K., Masui, S., Takeoka, H., Ikematsu, H., and Kashiwagi, S. A randomized, controlled trial comparing traditional herbal medicine and neuraminidase inhibitors in the treatment of seasonal influenza. 2014 Jan;35(1):87-99. If you take birth control pills along with peony, use an additional form of birth control such as a condom. Monograph. Am J Nephrol 2000;20:145-8. Abe K, Higurashi T, Takahashi M, et al.